Cannabidiol is a molecule contained in hemp. It is used to conceive CBD which acts against the evils that can generate gastritis. To better understand the effects of this substance on gastritis, it is necessary to know the virtues that allow it to fight against this evil. A preclinical study in the British Journal of Pharmacology stated that CBD might help alleviate vomiting & nausea caused by treatments, like chemo. Learn more. Stomach problems are a potential side effect of CBD, but it’s more likely other ingredients in gummies and oils causing your issue: here’s how to fix it.
Does CBD have any effect on gastritis?
Gastritis is one of the most painful conditions that human beings can suffer from. This ailment leads to unbearable stomach pain in the sufferer. Until now, very few natural treatments have been able to relieve the symptoms of this disease. It is then appropriate to ask whether CBD manages to curb it. This questioning must be answered in the affirmative. CBD has many properties that allow it to act effectively on the endocannabinoid receptors of the human body.
WHAT IS GASTRITIS
Gastritis is a gastrointestinal condition resulting from inflammation of the stomach lining. This is then categorized in the group of inflammatory diseases of the gastrointestinal tract. It may be a condition that occurs on an ad hoc basis in your body. In this case, it would be considered gastroenteritis caused by a viral or bacterial body. Gastritis also can develop into a chronic condition. If it is caused by a pathological agent, it will be observed swelling of the stomach wall. Thus, it is a stomach extension that can be prolonged over time.
When it occurs in an individual, it causes several symptoms to appear. The main one is swelling, and it is from this that almost all other symptoms arise. Among the latter, it can be cited the pains as well as the discomfort in the stomach. It must be understood that these types of pains are usually equated to excruciating burns. Indigestion, lack of appetite, increased stomach acidity, nausea, and vomiting are other severe symptoms of gastritis. It is also not uncommon to encounter patients with dark stool or diarrhea due to this autoimmune condition.
From the information put forward above, it is clear that gastritis is quite capable of causing serious damage to the human body when not treated properly. Therefore, it increases the chances of the patient developing stomach cancer. It is also capable of turning into a more severe form of gastritis. The latter is called erosive gastritis. It is known to completely wear away the gastric lining of the stomach.
WHAT ARE THE DIFFERENT TYPES OF GASTRITIS?
Scientific research has provided insight into how gastritis works. These experiments have also offered the doctor the chance to discover all the existing forms of this condition.
Thus, the most well-known variant of gastritis is acute gastritis. This one is known to occur promptly. The direct cause of such a condition lies in the use of non-steroidal anti-inflammatory drugs. This causes the body to inhibit the enzyme that synthesizes eicosanoids in the stomach area. This results in the formation of a good number of gastric ulcers. In addition, you need to understand that physiological stress caused by hypoxia or other trauma can cause acute gastritis.
The second most well-known form of this condition has been given the name chronic gastritis. It is known to occur slowly over the long term. Certain diseases and autoimmune disorders are the main causes of chronic gastritis. These immune deficiencies are characterized by creating proteins and antibodies that perceive the stomach as a foreign body to the body. Since their role is to protect the body against external threats, they begin to damage its lining. Many experiments have shown that autoimmune gastritis occurs in most cases in patients with Hashimoto’s disease. People with type 1 diabetes and certain vitamin B12 deficiencies are also prone to this condition. It should be added that this form of gastritis is known to penetrate bile in the stomach. This due to connective tissue disorders and other liver insufficiencies. Advancing age is also a participating factor in the onset of chronic gastritis. This is quite normal since, with time, the stomach lining becomes increasingly thin.
HOW CAN CANNABIS HELP WITH GASTRITIS?
At its core, the human body is made up of endocannabinoid receptors. This has allowed researchers to deduce that the body synthesizes even some cannabinoids. The receptors involved are distributed throughout the body’s organs and nervous tissue. In addition, many of the functions of the endocannabinoid system are directly related to the stomach. This is why treating gastritis with CBD consumption is a completely safe and effective option.
Furthermore, CBD provides the same benefits to people suffering from this condition as conventional medications. However, it does not cause the unwanted side effects that conventional treatments do. Thus, CBD can be used for:
- Reduce the symptoms of gastritis
In reality, cannabis has virtues that allow its consumer to reduce nausea and vomiting. Indeed, the THC contained in CBD allows this product to directly affect the areas of the brain in charge of triggering the release of stomach contents.
- Reduce inflammation
Above, it has been said that inflammation of the intestinal wall is the main symptom of gastritis. Since CBD has anti-inflammatory properties, it is very effective in this particular case.
Is it possible to self-prescribe CBD for gastritis?
CBD is certainly excellent, but it is not safe to self-prescribe it. So, avoid consuming it without a specific prescription and the approval of your doctor. Instead, it is advisable to approach a doctor to evaluate and determine the proper dose of CBD.
Does CBD completely cure gastritis?
CBD primarily treats the symptoms of gastritis. It reduces them until they disappear. However, when taken regularly, it is not unthinkable that it may not completely cure this ailment.
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CBD Oil for Gastritis – August 2022
Commonly prescribed medications and over-the-counter drugs for gastritis include omeprazole, rabeprazole, lansoprazole, dexlansoprazole, esomeprazole, and pantoprazole (6) . These drugs are some of the most potent inhibitors of stomach acid.
However, these medications may have side effects , such as iron and B12 deficiency, increased risk of fractures, pneumonia, and Clostridium difficile infections (7) . They can also be quite expensive over the long-term.
Clostridium difficile infections may cause diarrhea and eventually develop into a life-threatening medical condition .
Doctors may also prescribe antacids to treat gastritis by neutralizing stomach acid and providing pain relief. However, these drugs may result in constipation or diarrhea (8) .
A 2020 study in the International Journal of Molecular Sciences outlined CBD’s role in preventing and treating gastrointestinal disorders, like irritable bowel syndrome (IBS) and gastrointestinal cancer (9) .
The study demonstrated CBD’s anti-inflammatory properties in mice models of intestinal inflammation.
Gastritis is a collective term that refers to the inflammation of the lining of the stomach (10) .
Research in the Journal of Molecular Medicine evaluated CBD’s effects on an inflammatory bowel disease like ulcerative colitis (11) .
The authors found that CBD had anti-inflammatory properties beneficial for the inflamed gut. They also reported that CBD, a “likely safe compound,” prevented experimental colitis in mice.
Despite CBD’s purported health benefits on the digestive tract , it is essential to note the side effects of CBD use. These effects include diarrhea, changes in appetite or weight, and tiredness (12) .
CBD for Inflammation
A 2019 review archived in the journal Antioxidants stated that CBD had anti-inflammatory and antioxidant properties (13) .
The authors also mentioned CBD’s promise in treating disorders associated with inflammation and oxidative stress, such as cancer, cardiovascular, metabolic, and neurodegenerative diseases.
Another study documented in the journal Future Medicinal Chemistry discussed CBD’s effects on non-obese and diabetes-prone female rodents (14) .
The researchers found that CBD had anti-inflammatory effects that could help prevent type 1 diabetes.
CBD for Nausea
Common symptoms of gastritis include nausea and vomiting (15) .
Preclinical research showed that CBD might be useful in treating vomiting and nausea caused by chemotherapy and other treatments (16) .
A study archived in the British Journal of Clinical Pharmacology evaluated the effects of a dose containing CBD and tetrahydrocannabinol (THC) on patients with chemotherapy-induced nausea and vomiting (17) .
The researchers found that CBD and THC were well-tolerated and had antiemetic (vomit-preventing) properties.
They also observed that patients who received the cannabis-based medicine had better protection against delayed chemotherapy-induced nausea and vomiting.
CBD and THC are derived from the Cannabis sativa plant. However, unlike CBD, THC may get individuals high because of its psychoactive properties.
THC mainly comes from marijuana, a variant of the cannabis plant. Despite THC’s suggested benefits, medical marijuana use is not legal in the entire United States (18) .
CBD for Ulcers
Untreated gastritis may result in stomach ulcers and bleeding or stomach perforation (19) .
A 2018 study in the journal Phytotherapy Research evaluated CBD’s effects on oral wound healing (20) .
Standardized ulcers were induced in 60 rats. They were injected with 0mg (control), 5mg, and 10mg of CBD per kilogram of each rat’s body weight daily.
The researchers discovered that CBD had anti-inflammatory effects on the early phase of wound healing. However, they noted that their findings were insufficient to conclude that CBD use could improve oral traumatic lesions.
CBD as a Painkiller Substitute
The regular use of painkillers and nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, may result in gastritis and ulcers (21) .
Meanwhile, s tudies showed that CBD products might have analgesic effects. Hence, they may be used as substitutes for painkillers.
A study published in the journal Postgraduate Medicine revealed that CBD improved chronic pain in participants using opioids for pain management (22) .
One hundred thirty-one patients were included in the study. The researchers found that half of the study sample was able to reduce opioid use eight weeks after adding CBD to their medication regimen.
Participants who used CBD reported improvements in their quality of life. Their chronic pain and sleep quality also improved.
In another research, results indicated that CBD had analgesic and anxiolytic (anxiety-reducing) effects (23) .
Three hundred ninety-seven individuals were prescribed CBD. Participants who had non-cancer pain reported improvements in their pain.
Meanwhile, those who had mental health symptoms experienced alleviation of their depression and anxiety symptoms.
CBD was well-tolerated, and the participants did not report any adverse effects. Other CBD benefits include improved sleep and appetite.
How CBD Oil Works to Alleviate Symptoms of Gastritis
A study documented in the PLOS One Journal evaluated how CBD purportedly reduces intestinal inflammation (24) .
Eighteen participants were included in the study. The results revealed that CBD might interfere with enteroglial-mediated interactions in an intestinal inflammatory environment.
Enteric glial cells make up the enteric nervous system, a regulatory system responsible for gastrointestinal function (25) .
According to the study, CBD was involved in the downregulation of the protein S100B, resulting in reduced intestinal damage during acute and intestinal inflammation.
S100 proteins have a vital role in mediating innate and acquired immune response s (26) . These responses significantly contribute to the development of chronic inflammatory diseases.
It is believed that CBD’s interaction with the endocannabinoid system (ECS) may be related to its anti-inflammatory properties.
The ECS has an essential role in maintaining the body’s natural harmony. To fulfill this function, it interacts with several organs and systems in the body, such as the endocrine and immune systems (27) .
A study conducted in 2019 outlined the role of CBD and the ECS’ cannabinoid receptors in inflammation (28) .
Research found that CBD was a weak agonist of the cannabinoid receptor 1 ( CB1 receptor ) in humans and mice. It also stated that CBD demonstrated inverse agonism of the cannabinoid receptor 2 (CB2 receptor) .
An agonist is a substance that mimics another substance’s action, stimulating an action (29) .
The researchers found that the activation of cannabinoid receptor 2 reduces oxidative stress and inflammation.
They also found that CBD’s anti-inflammatory activity involved the reduction of cytokine levels, the inhibition of T-cell proliferation, the induction of T-cell apoptosis, and the migration of immune cells.
Cytokines are molecules that direct cell movement to sites of inflammation, trauma, and infection (30) .
T cells contribute to sustained inflammation by producing proinflammatory cytokines (31) .
Apoptosis is programmed cell death vital in removing unnecessary or abnormal cells (32) .
The Pros and Cons of CBD Oil for Gastritis
- Previous studies showed CBD’s positive effects on symptoms associated with gastritis and other conditions related to the digestive system .
- Compared with conventional drugs prescribed for gastritis, CBD’s safety profile is more favorable (33) .
- There are no reported cases of human or animal dependence on CBD (34) . Hence, individuals considering using CBD to treat their gastritis should not worry about developing a dependence on the substance.
- Researchers should further investigate CBD’s effects on gastritis.
- Despite the benefits of CBD , it still has side effects, such as diarrhea, tiredness, and changes in weight or appetite (35) .
- Policies from the United States Food and Drug Administration (US FDA ) do not support CBD as therapy for medical conditions other than epilepsy.
How CBD Oil Compares to Alternative Treatments for Gastritis
A study archived in the Sultan Qaboos University Medical Journal investigated honey’s antibacterial effects on the bacterium Helicobacter pylori ( H. pylori) , the common cause of several digestive issues, such as gastritis and a very common contributor to the development of gastric and duodenal ulcers (36) .
The researchers concluded that some honey brands had antibacterial properties useful in treating H. pylori infections.
They also noted that when honey was used with antibiotics, such as clarithromycin and amoxicillin, there was no synergy or antagonism.
They recommend that honey may be useful as an adjunct therapy. It helps reduce the elimination time of H. pylori bacteria from the stomach lining of individuals with gastritis or duodenal ulcer.
Similarly, CBD was found to have antibacterial properties. Research in 2019 reported CBD’s efficacy in killing a range of Gram-positive bacteria (37) .
The researchers suggested that, given CBD’s anti-inflammatory properties and proven safety in humans, the substance held promise as a new antibiotic.
They also noted how CBD retained its efficacy against bacteria that became highly resistant to other traditional antibiotics.
Gram-positive bacteria are called such because they give a positive result when put under the Gram stain test (38) .
How to Choose the Right CBD for Gastritis
A previously cited study showed the efficacy of THC or medical cannabis on gastritis symptoms, such as vomiting and nausea. However, as mentioned earlier, THC use is not legal in all US states.
Full-spectrum CBD oil contains all the Cannabis sativa plant components, including terpenes, flavonoids, fatty acids, essential oils, and trace amounts of THC.
It is suggested that full-spectrum oils provide full therapeutic benefits because of the synergy of all the active ingredients of the cannabis plant. This mechanism is called the entourage effect.
The THC content of full-spectrum CBD products (less than 0.30%) is allowed by federal laws. However, this minimal amount may still be detected by drug tests.
Individuals who want to purchase CBD products free of THC may buy broad-spectrum CBD. This type of CBD oil has all the ingredients of the full-spectrum oil except for THC.
For pure, isolated cannabidiol, CBD isolates may be purchased.
Full-spectrum CBD oils are recommended for gastritis treatment. Still, individuals are encouraged to speak to a medical professional before purchasing any CBD product.
It is also essential to research if a manufacturer or dispensary is credible and authorized by the government to sell CBD to avoid buying illegitimate products.
CBD Dosage for Gastritis
Currently, no standard dosage chart has been developed for CBD in treating gastritis. However, it is recommended to begin with a small amount of CBD .
If no adverse effects are seen, the dosage may be increased gradually until the desired effect is achieved.
Individuals using CBD for gastritis are encouraged to keep a journal of their reactions to the substance. They may refer to this journal during consultations with their physician.
Before adding CBD to one’s gastritis medication regimen, it is recommended to inform a medical professional first.
How to Take CBD for Gastritis
There are several options when taking CBD for gastritis.
Some formats, such as CBD oils and tinctures (drops), allow individuals to take CBD directly. Tinctures may be applied sublingually, or under the tongue, for added efficacy.
CBD oils may be mixed with food or beverages to mask CBD’s naturally grassy taste.
CBD pills, gelcaps, capsules, edibles, and gummies may be ingested. This format also allows people with gastritis to conveniently bring their CBD medication with them anywhere.
This format is also appropriate for people with gastritis problems who want to take a consistent dosage of CBD.
CBD topicals, such as balms, salves, lotions, and ointments, may also be used. During episodes of abdominal pain or upset stomach , these topicals may be massaged into the affected area.
Some topicals contain soothing ingredients, such as peppermint and menthol, for added pain relief.
For instantaneous effects, CBD may be inhaled via vape pens. However, vaping CBD may be challenging, as it is hard to determine how much CBD was already taken.
In some individuals, vaping may also cause lung problems (39) .
According to Johns Hopkins Medicine, gastritis occurs when the stomach lining gets swollen (40) .
Gastritis may be caused by drinking excessive amounts of alcohol, eating spicy food , extreme stress, smoking, and long-term use of pain and fever medications.
Bacterial infections , major surgeries, and traumatic injuries or burns may also cause gastritis.
Gastritis may be classified as acute gastritis or chronic gastritis . Gastritis symptoms include the following (41) :
- Stomach upset or pain
- Belching and hiccups
- Bloating or gas
- Bleeding of the belly or abdomen
- Loss of appetite
- Nausea and vomiting
- Blood in the vomit or stool
- Weight loss
When untreated, gastritis may also result in other more severe health complications. These conditions include peptic ulcer disease (painful sores in the upper digestive tract) and tumors that could lead to stomach cancer .
A study also found that gastritis was associated with an increased prevalence of panic attacks, social phobia, major depression, and mood disorders (42) .
Previously mentioned studies found that CBD might be useful in treating gastritis symptoms, such as inflammation, nausea, and pain.
Compared with conventional medications prescribed for gastritis, CBD is generally safe because of its minimal side effects.
Like honey, CBD was found to have antibacterial properties.
CBD also comes in different forms and formulations, giving individuals with gastritis several options.
While CBD has been deemed for its favorable safety profile, in some individuals, CBD oil may be hard on the stomach.
For a more efficient treatment, it is best to consult with a healthcare provider before taking any CBD product for gastritis.
Here’s What to Do if Your CBD Edibles are Giving You Stomach Issues
There are a multitude of reasons you might be taking CBD, but getting some side effects can easily make it feel like the benefits aren’t worth it. Having stomach issues is one of the more common groups of side effects from CBD products, including edibles but especially with oils. However, there is good news: most of the time, the side effect comes from other ingredients in the product and not the CBD itself. And if it is the CBD, chances are your dosage is too high and this is the cause of the issue.
But why does it happen? How can you tell what’s causing the problem? And what should you do about it?
- CBD can cause diarrhea and gastrointestinal distress, but this isn’t very common and is usually linked to high doses.
- If you get stomach ache from edible gummies, it’s probably another ingredient in the gummies causing the issue.
- MCT or coconut based CBD oils can cause stomach aches too.
- Try another type of CBD product (such as a different edible, vape pen or capsule) and reduce your dose if you’re experiencing problems.
- Drinking chamomile or ginger tea, taking acetaminophen or using Pepto-Bismol can give you immediate relief.
Stomach Issues are a Common Side Effect of CBD
There have been loads of clinical studies on CBD, and – as with all new treatments – side effects are one thing they always consider. A review of the evidence from 2017 went through all of the relevant animal and human data, and generally found that the side effects were minimal and limited, generally being a plus-point for CBD compared to other treatments. However, like all treatments that actually do something, it does have some side effects.
The research covered in the paper identified a few side effects in particular, tiredness, diarrhea and changes in appetite and weight. Generally speaking, CBD is helpful for gastrointestinal issues, but this means it interacts with this area of the body and makes side effects possible, and gastrointestinal distress is often reported.
Note that CBD can also interact with other medications, in the same way as grapefruit, so you should avoid using it if your medication has the “grapefruit warning.”
Is it the CBD or the Edible?
While CBD can cause gastrointestinal issues by itself, it seems to be related to high dosages more than a necessary impact of CBD. This means that if CBD gummies are giving you a stomach ache, there are two major possibilities: either you’re taking too much CBD when you eat some, or it’s something else in the edibles causing your problem.
Assuming you’re taking CBD for some other purpose, the best approach is to try CBD in some other form. For example, you can try a different type of edible, a vape pen, flower, a capsule or even a tincture (although more on that in a minute). If this isn’t an option, you can try a much smaller dose of the edible to see if that still affects your stomach.
If you can find a different form of CBD to try, then you’ll be able to work out what the exact problem is. If you don’t experience the same symptoms with another type of CBD, then you know it was an ingredient in the gummy rather than the CBD. If you can only try a lower dose, if the symptoms aren’t as bad (or don’t appear) then it was probably related to the dosage you were taking.
CBD Oil is Likely Worse than Edibles for Your Stomach
If you’re having issues with edibles, you may be tempted to try the more traditional CBD oil instead, but you need to be cautious of some ingredients. MCT oil, for example, is known to cause stomach issues for some people, and most people who experience problems with stomach aches and CBD are using oil containing it. It’s also possible that CBD oil with coconut oil as a carrier could also cause problems.
There are many other carrier oils you can use with CBD, so it’s worth trying other options if you also have problems when consuming some oils but still want to take CBD in this way. Another potential issue is the minimal regulation for CBD products, so it’s important to buy your oil from reputable sources, ideally with a lab report to confirm purity and the cannabinoid mix in the oil.
How to Avoid Problems in Future
If you’ve been having problems with stomach aches from CBD edibles, the solutions follow directly from the discussion above.
First, try CBD in another form. It’s more likely that it’s something in the gummy other than CBD which is causing your issue. Try a non-MCT or coconut-based oil, vaping or capsules. Even a different type of edible may be much more tolerable. If you find that something else works, it’s worth looking at the specific ingredients in the gummies that caused you problems: you might be able to identify the component that’s giving you issues and even try other gummies not containing it in future.
Secondly, try lowering your dose of CBD. It’s less likely that the CBD itself is causing you issues, but research shows that it is possible, especially with higher doses. It’s likely not ideal to have to reduce the amount of CBD you’re taking to help with whatever the issue is, but if you lower the dose you might be able to find the right balance for relief without unpleasant side effects.
Both of these solutions unfortunately involve a lot of trial and error, but once you’ve worked out the exact problem then you’ll be in a much better position.
How to Soothe Your Stomach
If you’re in pain right now and you want help for that, it’s best to follow standard advice for stomach problems. If it’s cramping related to diarrhea, you can try Pepto-Bismol, and even simple pain relievers like acetaminophen or ibuprofen can help with stomach pains of all types. Alternatively, drink chamomile, peppermint, ginger, fennel or cinnamon tea, do some gentle exercise (such as yoga) and eat anti-inflammatory foods (such as blueberries, leafy greens, tomatoes, cherries and more).
Luckily for people who want to continue using CBD, it’s more likely that another ingredient in the oil or gummy is the cause for your stomach ache. The challenge is identifying what it is or which products don’t cause you issues, so you can easily avoid problems in future. If your dosage of CBD is too high, you may need to reduce it, but it’s unlikely you will have to stop taking CBD altogether for relief from other issues.