Can I Take CBD Oil With Antibiotics

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Researchers from the University of Southern Denmark have found that cannabidiol (CBD) combined with antibiotics has a more powerful effect in treating cert | Cannabis Sciences Cannabis oil makes antibiotics more effective, study finds Dr Sigrun Lange, Senior Lecturer in the Department of Biomedical Sciences, led a major study revealing that cannabis oil (CBD) can

CBD Makes Antibiotics More Effective

Researchers from the University of Southern Denmark have found that cannabidiol (CBD) combined with antibiotics has a more powerful effect in treating certain infections than antibiotics alone.

For the study, the researchers analyzed how different compounds work against various bacteria, including Staphylococcus aureus, a gram-positive bacteria known to cause serious infections like pneumonia and bacteremia (bloodstream infection). They also investigated treatment for gram-negative bacteria.

In particular, they analyzed different cell cultures with the bacteria alongside CBD, antibiotic bacitracin (BAC), CBD and BAC, ethyl alcohol, or nothing at all. Each cell culture was subjected to the dugs for two and a half hours.

In the end, the researchers found that top shelf CBD flower was able to increase the effects of BAC against S. aureus and other gram-positive bacteria. CBD oils tend to vary though and you have to make sure to pick the best cbd oil for you. The combination, however, was not effective against gram-negative bacteria.

As for how the combination works, the researchers noted that cell cultures treated with it underwent alterations in the morphology of their cells when compared to other treatments. Changes included a lack of cell separation during cell division, as well as downregulation of cell division gene, ezrA.

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The findings are promising, especially given the global threat of antibiotic resistance for treating multiple diseases and infections.

“When we combined CBD and antibiotics, we saw a more powerful effect than when treating with antibiotics alone. So, in order to kill a certain number of bacteria, we needed less antibiotics.” state the researchers.

Before the combo may be prescribed instead of antibiotics alone, however, more research is needed to understand how CBD and BAC work in both animals and humans, and whether they have the same effects.

These results are not the only findings to show the potential of cannabis products in treating bacterial infections. Research from earlier this year, for example, has shown that another cannabinoid, known as ‘cannabigerol’ (CBG), can effectively neutralize Staphylococcus aureus- both in Petri dishes and in mice.

Cannabis oil makes antibiotics more effective, study finds

Dr Sigrun Lange, Senior Lecturer in the Department of Biomedical Sciences, led a major study revealing that cannabis oil (CBD) can increase the effectiveness of antibiotics. Professor Jimmy Bell from the Research Centre for Optimal Health was also involved in the study.

The study is the first of its kind to assess the supposed effects of CBD on the release of membrane vesicles (MVs), components that are released from bacteria and can transfer material for bacterial communication as well as functioning as traps for antibiotics.

Researchers from a number of UK universities were involved in the study which was led by University of Westminster researcher Dr Lange, and showed that CBD could, through this newly discovered mode of action, increase the effectiveness of a range of antibiotics depending on the type of bacteria.

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The team tracked the release of the membrane vesicles from the bacteria with and without CBD, the ingredient within the cannabis plant that does not affect the mind, and confirmed that CBD both affected the number of MVs released as well as the structure of the MVs released from bacteria.

The research project tested the effects of CBD on different types of bacteria with either thick or thin cell walls, and found that CBD particularly reduced the release of MVs from thin cell walled bacteria and also significantly increased effectiveness of killing bacteria of this kind in the presence of antibiotics.

From this discovery, the team concluded that using CBD in combination with specific antibiotics may be used as an agent to target and make bacteria sensitive to antibiotic treatment and reduce antibiotic resistance.

Speaking about the study, Dr Lange said: “The antibacterial properties of CBD have been known for some time, but no one knew how it worked. Based on our previous work which established that CBD is a potent, previously unrecognised regulator of vesicle release we have now demonstrated that CBD is very effective at increasing antibiotic effects through changes in membrane vesicle composition and release in bacteria.

“Our findings highlight that CBD application, in conjunction with antibiotic treatment, may be an interesting adjunct to the development of novel treatment to help reduce antibiotic resistance, especially given that antibiotic resistance is on the rise and predicted to be a global health disaster.”