CBD Oil And Fluid Retention


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Edema, or swelling from fluid retention, can appear from injury or inflammation. I take a look at whether or not CBD, a known anti-inflammatory, can help. Latest medical research – can cannabis treat edema? Learn the THC:CBD ratios. Try CannaKeys research tools. 1 Week Free Trial. The anti-inflammatory effects of weed means that it can help reduce swelling. Learn everything to know, along with strains that can help.

CBD Oil For Edema

Fluid retention can appear from injury or inflammation. CBD has been known for its great anti-inflammation properties. But can CBD oil actually help to treat edema? Read on and find out.

Table of Contents

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What is CBD?

CBD (or cannabidiol) is a non psychoactive compound from cannabis plant. It will not give you the well-known euphoric effect that THC has. CBD is famous for its health benefits. The list of CBD’s benefits and what CBD is proven to help with is quite long: CBD relieves pain and inflammation; reduces anxiety and depression; reduces acne; reduces oxidative stress; calms epilepsy. Furthermore, I found several articles stating that CBD might help with some condition by reducing psychotic symptoms, prevent diabetes, benefit heart health and alleviate cancer-related symptoms. However, the research on this topic is quite limited, so these benefits are not scientifically proven, but there are many testimonies online from people that say that CBD has definitely helped them.

What are the main causes of edema?

Fluid retention, or edema, is caused by many things including 6 major factors. Not drinking enough water to flush out your system can cause retention – if you do not drink water, your body will then hold on to it (or retain it) to survive and keep organs functioning. Deficiencies of magnesium also cause water retention. Magnesium is a very important nutrient in our body and we need to intake at least 200 milligrams daily. Not doing so may lead to swelling. Not getting enough potassium may cause our organs to not function correctly and cause our bodies to hold on to water, since those very organs are what keep our water storage functioning. While vitamin B6 may also cause water retention, reasoning as to why was not supplied in the article. Regardless, this can be avoided by eating certain foods rich in B6 vitamins. Consuming too much salt also causes edema. If you eat too much without drinking water to flush it out of your system, you may hold on to that water weight.

With that said, processed foods are often flavoured with excessive salt and sugars, which our bodies aren’t meant to process. By consuming these things, your body is again getting too much of what it doesn’t need and in turn will retain water. Finally, drinking water, or not enough, will also impact your body! The more water you drink, the less your body will hold on to. Drinking water flushes out your system and helps your body not retain, so everything runs smoother and theoretically functions correctly. If retaining water, movement or exercise helps let go of those fluids. Also, elevating legs, eating more naturally occurring foods like fruits and vegetables, not wearing constricting clothes and avoiding hot showers all help in ridding ourselves of edema.

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CBD oil and fluid retention: What’s going on?

CBD oil has shown to be a good pain reliever and to have anti-inflammatory and anti-bacterial properties. However, there is limited research available on this topic, so it is really hard to tell if CBD actually helps with fluid retention. Preliminary research suggests that CBD may reduce food intake and boost metabolism, which could promote weight loss, but it is still not clear if it works from fluid retention. And is CBD a diuretic? The research states: “The present studies demonstrate that doses of CB agonists that produce these effects also reliably increase diuresis. Diuretic effects of several CB agonists were measured in female rats over 2 hours immediately after drug injection, and results were compared with hypothermic effects.” So from that we may assume that there are some effects that may potentially be helpful. But this research was held on rats, so it is not proved that the same effect will be for people.

Does CBD help treat edema?

Edema, which is also known as fluid retention, is the buildup of fluid in the body’s tissue. Most commonly, it affects legs or arms. Symptoms of edema can include skin which feels tight, the area may feel heavy, and affected joints may be hard to move. Other symptoms depend on the underlying cause of the appearance of edema. CBD is known to decrease the inflammation in the body. Edema is a good example of inflammation and based on many testimonies from people that used CBD in their treatment, I can tell that CBD can actually be helpful in dealing with edema. However, it should not be treated as the only medication from edema.

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Can CBD oil cause water retention?

CBD has a physical effect on the body and brain. After you consume this cannabinoid, it binds with the ECS receptors of the endocannabinoid system, interacting with the central and peripheral nervous system, without creating any psychoactive effects. Scientists have concluded that CBD oil is safe for human consumption and it comes with only a few minor side effects. While cannabinoids affect everyone a bit differently, it looks like the majority of CBD users can consume CBD oil without any adverse reactions. While doing my research, I couldn’t find any specific information about CBD causing water retention in the human body. So from what I’ve found, CBD oil is safe and may cause only minor side effects, which do not include water retention.

Edema – Cannabis THC : CBD Ratios

To see a full dashboard with study details and filtering, go to our DEMO page.

As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.

CannaKeys has 1 studies associated with Edema.

Here is a small sampling of Edema studies by title:

  • Anti-Edema And Analgesic Properties of Δ9-Tetrahydrocannabinol (THC)

Components of the Edema Research Dashboard

  • Dosing information available for Edema
  • Chemotype guidance for treating Edema with cannabis
  • Synopsis of cannabis research for Edema
  • Individual study details for Edema

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Overview – Edema

Description of Edema

Edema is caused by the leakage and build-up of fluids from the capillaries (smallest blood vessels) and while it can occur in any part of the body it is usually worse (due to gravity )in those parts of the body closest to the ground such as ankles or feet for example. Underlying condition may include congestive heart failure, lymphatic blockages, liver disease, kidney failure, burns, pregnancy, or certain pharmaceutical medications (e.g. steroids, estrogen, non-steroidal anti-inflammatory drugs) for example. Orthodox treatment options in milder cases include elevation of affected limb, compression stockings, dietary changes (e.g. reduction of processed salts), upward stroking massage; and depending on underlying condition and in more severe cases involve the use of diuretics (aka water pills).

Disease Classification

Condition: Edema
Disease Family:
Organ System: Cardiovascular System, Integumentary System, Respiratory System
ICD-10 Chapter: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
ICD-10 Code: R60

Edema Symptoms:

Swelling under the surface of the affected tissues, shinny stretched surface areas of the affected skin, pitting edema (any form of pressure will retain an imprint)

Also known as:

Drug Interactions

THC Interaction with Pharmaceutical Drugs

  • THC can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol, for example.
  • THC is metabolized by and an inhibitor of a number of enzymatic liver pathways referred to as cytochrome P450. There are more than 50 enzymes belonging to this enzyme family, a number of which are responsible for the breakdown of common drugs such as antidepressants (e.g. amitriptyline, doxepine, fluvoxamine), antipsychotics (haloperidol, clozapine, stelazine), beta-blockers (e.g. propranolol), bronchodilators (e.g. theophylline), or bloodthinners (e.g. warfarin). Thus patients taking these classes of medication may find that THC increases the concentration and effects of these drugs as well as the duration of their effects.
  • Clinical observation suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.

CBD Interaction with Pharmaceutical Drugs

  • CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects.
  • Groups of drugs affected include: anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
  • Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD

Dosing Considerations

THC Dosage Considerations

  • THC micro dose: 0.1 mg to 0.4 mg (0.001mg/kg to 0.005mg/kg)
  • THC low dose: 0.5 mg to 5 mg (0.006mg/kg to 0.06mg/kg)
  • THC medium dose: 6 mg to 20 mg (0.08mg/kg to 0.27mg/kg)
  • THC high dose: 21 mg to 50+ mg (0.28mg/kg to 0.67mg/kg)

CBD Dosage Considerations

  • CBD low dose: 0.4 mg to 19 mg (0.005mg/kg to 0.25mg/kg)
  • CBD medium dose: 20 mg to 99 mg (0.26mg/kg to 1.32mg/kg)
  • CBD high dose: 100 mg to 800+ mg (1.33mg/kg to 10.7mg/kg)
  • (upper limits tested ~1,500mg)

Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.

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Does Weed Reduce Swelling?

Using cannabis as medicine has gained more acceptance over the past twenty or so years. Today, millions of Americans support legal cannabis, and more than five million are registered medical patients .

This massive growth of the medical cannabis industry is due to the many positive effects users experience when using their medicine. One of those many benefits is medical cannabis’s ability to reduce and control inflammation throughout the body.

Does Cannabis Reduce Swelling?

Cannabis reduces swelling. Researchers and studies on medical cannabis have long touted and promoted anti-inflammatory benefits for medical cannabis patients.

A 2008 study showed that the cannabinoids present in medical cannabis products are helpful at reducing inflammation throughout the body. Regardless of whether that inflammatory response comes from a condition like rheumatoid arthritis, IBS, or an autoimmune disorder that shows in the form of swelling on the surface of the skin like psoriasis or eczema, the swelling associated with the building and breaking down of muscles when it comes to athletic performance and fitness, or even the swelling the happens in response to an injury, like an ankle sprain.

This study was quick to point out that while the cannabis plant does have cannabinoids that intoxicate users, the vast majority of cannabinoid compounds present in the cannabis plant have other valuable effects on the rest of your body.

Another more recent study, published in 2018 , showed that isolating non-psychoactive cannabinoids, like CBD, had a measurable effect on reducing all-cause inflammation throughout the body. Not only did the CBD products reduce all-cause inflammation throughout the body with little to no side effects, but it was proven effective when it comes to pain relief, easing chronic inflammation, and profoundly impacting the immune system. These studies show that cannabis and the cannabinoids present in marijuana and medical cannabis products have powerful anti-inflammatory properties.

More federally funded research studies need to be done on the exact doses, compounds, and processes by which medical cannabis can be used to reduce all-cause inflammation throughout the body. However, it’s worth noting that researchers already do know quite a bit about THC and CBD, the two most well-known and researched cannabinoid compounds, when it comes to reducing inflation.

While everyone is different, and will thus require different doses and frequency of doses to treat the specific inflammation that ails them, a dose of CBD or THC to ease inflammation will usually kick in after about 15 minutes. From there, your weight, sex, BMI, tolerance, and a variety of other factors will need to be considered when it comes to how long your current dose will last and when you’ll need to dose again to keep the swelling down. However, a good rule of thumb is to dose CBD every three to four hours to keep the swelling at bay.

Potential Risks and Drawbacks

When it comes to using cannabis products to ease inflammation, the drawbacks and risks are few and far between. CBD and THC, the two primary cannabinoids present in medical cannabis products for inflammation reduction, have been rigorously tested in human and animal studies. They’re proven to be effective in easing inflation, pain, and a variety of other ailments and are pretty much harmless as long as they’re used as directed.

CBD is non-psychoactive, so it won’t affect your ability to perform day-to-day tasks. On the other hand, THC-infused products have an apparent downside compared to CBD. THC, while effective at reducing pain and inflammation, is psychoactive. That means that while THC is effective, you’ll be somewhat limited in what you can do while using it.

It’s important to note that everyone is different when it comes to medications, especially cannabis. You should consult with your certified cannabis doctor before making any changes to how you treat inflammation throughout the body. Everyone is different and consulting with your personal doctor will help you get the most out of your medical cannabis.

Aside from that, there really aren’t many downsides when it comes to using either CBD or THC to reduce swelling.

Download Free Guide to THC

Terpenes and Flavonoids for Swelling

While cannabinoids like THC and CBD play a significant factor in relieving pain and inflammation throughout the body, the terpenes and flavonoids in cannabis products can also play a role. Think of these terpenes like boosters to the cannabinoids compounds, a compound that can amplify effects.

Some of the most effective terpenes for dealing with all-cause inflammation throughout the body are as follows:

Free Cannabinoid and Terpene Guide

Best Cannabis Strains for Swelling

The strain that works best for you is deeply personal. While these suggestions might be on point, others might not get the same benefits. On that note, you should always consult with you certified cannabis doctor and budtenders at your local dispensary to figure out what works best for you!

Let’s get right into it.


This Sativa-dominant strain is as unique in its genetics as its name. Spawned from a mix of Nepali indica, Thai Sativa, Colombian Gold, and Swiss Sativa lineages, this strain is about as CBD heavy as it gets without sacrificing the THC and entourage effect needed for dramatic results. Harlequin is known to be especially effective in treating and managing pain and inflation associated with arthritis and joint pain. We highly recommend this one when it comes to reducing pain and swelling.

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This deviation from the well-known and loved Girl Scout Cookies, Cronuts, improves the terpene profile. Packed full of beta-myrcene, beta-caryophyllene, and limonene, this strain is incredibly effective when it comes to easing and reducing chronic pain, swelling, and inflammation. If you’re dealing with swelling and inflammation throughout the body, then this strain is a go-to for finding some relief and managing your symptoms.

Charlotte’s Web

Originally developed to treat a young epileptic girl, this strain featuring her namesake is a high-CBD product that’s perfect for someone looking to avoid big doses of THC. With the THC content rarely exceeding .3 percent, the 20 percent of CBD content packs a powerful anti-inflammatory punch. This one is an excellent option for the patient looking at the benefits of medical cannabis without the psychoactive effects of THC. This strain is a perfect choice for someone looking to reduce pain and inflation without getting high.

Best CBD Products for Swelling

If you’re looking for an anti-inflammatory factor without the psychoactive effects of THC, then going with a CBD product is the way to go. Here are a few CBD-only products that we recommend checking out if you’re looking to deal with general inflammation throughout the body.

Aspen Green Full-Spectrum Hemp Extract

If you’re on the hunt for a full-spectrum CBD product, there are few finer on the market going into 2022 than Aspen Green Full-Spectrum Hemp Extract. Made from only USDA-certified organic hemp extract from Colorado, this product is chock full of terpenes and flavonoids that get to work in your body, combating inflammation. While it does contain trace amounts of THC, it’s not enough to negatively impact you when it comes to productivity.

Colorado Botanicals

When it comes to high-quality ingredients, responsible sourcing of the best possible cannabis plants, and top-notch products full of quality CBD, there are few finer brands on the market today than Colorado Botanicals. With high standards of extraction and powerful plant-based medicine packed into every bottle, we highly recommend their CBD products if you’re looking for a way to reduce inflammatory responses throughout the body.

Premium Jane Citrus CBD Tincture

If you’re looking for a CBD product that is as tasty as it is effective at treating inflammation and pain throughout the body, look no further than Premium Jane Citrus CBD Tincture. This CBD tincture is produced from top-notch Kentucky hemp, packed with terpenes like limonene and pinene, and has proven anti-inflammatory benefits when used in proper dosages. Not only does this full-spectrum tincture effective at treating pain and easing inflammation, but it has a delicious citrus taste to boot.

The Bottom Line

When it comes to easing inflammation naturally and without the use of synthetic, big pharma pushed mediation, medical cannabis is the way to go. The research that’s been done so far has been clear about the anti-inflammatory properties of cannabis. When it comes to easing all-cause inflammation throughout the body, from a wide variety of issues and medical ailments, there are few more natural treatments options than cannabis.

Frequently Asked Questions

Is cannabis more effective than ibuprofen for swelling?

While it’s impossible to say that cannabis is more effective than an NSAID like ibuprofen for swelling, the research indicates that it’s just as effective when used and dosed as directed . However, it’s worth noting that cannabis research is still in its infancy. It’s possible that in the next decade or so, cannabis may become the go-to treatment over medications like ibuprofen.

Can weed help my swollen feet?

Yes, cannabis can help reduce swelling throughout your body. If you’re looking for localized relief, you should consider getting a topical cream that you can apply directly to your feet. That will get the highest amount of cannabinoids into the areas affected most by the swelling.

Why is cannabis effective for swelling?

Cannabinoids, like CBD, have powerful anti-inflammatory effects. By interacting with the CB1 and CB2 receptors in the body, cannabis causes your cells to send less inflation-inducing signals. That means that no matter where the inflammation is in your body, cannabis reduces it in a significant and measurable way.

Article written by

Joe Evans Content Writer

Joe Evans is a journalist, writer, editor and contributor for Leafwell. He has, to date, more than 5,000 articles published online under his byline on topics like cannabis, local and National news, politics, automotive news, sports, pop culture and even a cult.

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