CBD Oil And Viagra Interaction

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Can you mix CBD and Viagra together? Despite the need for more research, it seems generally safe to combine CBD with Viagra. There is no research that CBD, a natural substance from the cannabis plant, may help treat ED, but it may help address anxiety. Your access to this site has been limited by the site owner If you think you have been blocked in error, contact the owner of this site for assistance. If you are a WordPress user with

Can You Use CBD And Viagra Together

Despite the need for more research, it seems generally safe to combine CBD with Viagra.

Can you mix CBD and Viagra Together? For those that use CBD products and the blue pill known as Viagra, it’s helpful to know the answer to this question

Marijuana and marijuana-derived products are becoming more and more popular all over the world, but few people know what CBD or viagra are or how they work. CBD (Cannabidiol) is the non-psychoactive compound found in cannabis, which you may already know by its other name, hemp.

It’s been used for centuries to treat various ailments, but it only became available in the U.S. without a prescription in 2018 after many years of research on the plant and its effects on patients with certain conditions, particularly chronic pain patients.

What Is Viagra?

Viagra is a medication that contains the active ingredient sildenafil. It’s used to treat erectile dysfunction (ED) in men. ED is when you can’t get or keep an erection. Viagra relaxes muscles and increases blood flow to particular areas of the body, which helps you get and maintain an erection. Men who have ED take viagra as needed before sexual activity.

Viagra has been prescribed for more than 20 years and is the most popular treatment for ED. It’s also available as a generic medication.

Viagra is manufactured by Pfizer Inc., was approved to market in the U.S. in March 1998, and became available on March 27, 1998.

What Is CBD?

Cannabidiol (CBD) is one of over 60+ cannabinoids found in cannabis plants. Unlike tetrahydrocannabinol (THC), it does not produce any psychoactive effects or feelings of being high. The FDA also recognizes CBD as a safe and effective medical treatment for children with epilepsy, anxiety, PTSD, autism, seizures, and diabetes. It can also be used to relieve joint pain and promote general health.

Along with THC, CBD produces the chemical compound called cannabigerol (CBG). CBG has been found to help regulate the human immune system’s reaction to viral infections such as influenza. It may also be effective against antibiotic-resistant bacteria that cause serious illnesses like MRSA infections and drug-resistant tuberculosis.

The University of Colorado Boulder suggests that CBD has anti-inflammatory properties that can help reduce inflammation associated with Crohn’s disease as well as other autoimmune diseases like psoriasis and arthritis.

In some experimental models, CBD benefits include acting as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic, and antipsychotic agent. As a result, CBD is a potential medication for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety, and schizophrenia. In trials on animals, it was found to assist in reducing discomfort.

Is It Safe To Take CBD And Viagra Together?

You may have heard that CBD can be used to treat a variety of ailments, but did you know that it can also be used in conjunction with other medications? That’s right, CBD can be stacked with other drugs to amplify their effects. But is it safe to take CBD and Viagra together?

It turns out that you can, but there can be a mild interaction between the two, so you’ll want to approach the combination with caution. The two substances work by different mechanisms, so they do not interact adversely with each other in serious ways, but you still want to use caution.

When combined, there is a chance that they will work synergistically, enhancing the benefits of both substances. Plus, because both substances act as vasodilators (drugs that expand blood vessels), taking them together has been shown to improve erectile function by increasing blood flow to the penis.

As always, consult your doctor before starting any new medication regimen or treatment plan. Although stacking CBD and viagra together is generally considered safe, you’ll always want to be aware of the possible interactions between each.

For example, because both treatments are vasodilators, taking them together could lead to dangerously low blood pressure if taken concurrently with alpha-blockers such as Hytrin® or Flomax®. If you are on these medications already, speak to your doctor about potential interactions before adding CBD into the mix.

Effects Of Taking Both

Although it’s generally safe to take both CBD and Viagra, they each have different effects. CBD may help reduce anxiety and stress, while Viagra is used to treat erectile dysfunction. When taken together, you may experience increased relaxation and improved sexual function.

There are some reports that the combination of the two can increase plasma levels in the body, especially if you’re taking Viagra on a daily basis.

However, it’s important to remember that everyone reacts differently to these substances, so be sure to start with a low dose and increase gradually as needed. Some people are more sensitive to the effects of drugs than others, and taking too much could lead to feelings of over-sedation or nausea.

In addition to Viagra, if you’re currently taking medication for a mental health condition such as depression or anxiety, speak with your doctor before mixing cannabis or any other substances with your prescription medications. It’s also worth noting that there are possible interactions between cannabis and certain medications such as blood thinners (anti-coagulants), clozapine (an antipsychotic), proton pump inhibitors (PPIs), and serotonin reuptake inhibitors (SSRIs).

While this blog post has touched on some of the most common questions about combining CBD and viagra, there are many variables that come into play when considering whether or not it is appropriate for you. Consult with your physician if you have any concerns about mixing the two in order to find out what would work best for you.

Viagra Side Effects

Viagra can cause a number of side effects, including headaches, indigestion, flushed skin, and changes in vision. It can also cause more serious side effects like chest pain, irregular heartbeat, and fainting. If you experience any of these potential side effects of Viagra, you’ll want to immediately stop taking the medication and call your doctor.

CBD is known to cause dry mouth, lethargy, and alterations in appetite. It can also interact with other medications you’re taking, so it’s important to talk to your doctor before using CBD to make 100% sure. CBD can cause increased sleepiness when taken in combination with caffeine or alcohol.

The effect of CBD on this medication isn’t entirely clear yet, and more studies need to be conducted. There haven’t been enough studies to determine the full extent of how much CBD interacts with Viagra or how these two drugs might work together.

If you’re on the fence about trying out the combination of these two products, you may want to avoid mixing these two medications, especially if you have an underlying heart condition because the combination could have dangerous effects on your heart rate and blood pressure levels.

Is It Possible To Overdose On Both?

It’s possible, but it would be very difficult to do so. The lethal dose of CBD is around 20,000 times the average dose, while the lethal dose of Viagra is only around four times the average dose. So, you would need to take a lot of both drugs to reach a lethal level. However, it’s important to remember that everyone reacts differently to medications, so it’s always best to speak with a doctor before starting any new medication regimen. What Are Some Potential Side Effects?:

It is important to remember that if one has taken more than the recommended dose of either drug, that emergency medical attention should be considered immediately. In addition to having an increased risk of overdose due to taking more than the recommended dosage of either drug on their own, there is also an increased risk if one has taken more than the recommended dosage of both drugs at once.

What Are The Side Effects Of CBD?

CBD can counter the psychoactive effects of THC and help with anxiety and stress. There are, however, a few side effects that may occur.

Mild nausea: Some people report feeling nauseous after taking CBD oil. This is likely due to the way your body metabolizes the cannabinoids; if you experience this effect, try taking CBD with food or another fatty meal.

Changes in blood pressure: Some users have reported an increase in blood pressure after taking CBD oil. If you already have high blood pressure or are concerned about your blood pressure increasing, be sure to speak with your doctor before starting a new supplement regimen with CBD oil.

Diarrhea: Diarrhea is another common side effect of CBD oil use. It’s important to note that diarrhea can be caused by many other factors besides using a supplement like CBD oil; if you’re experiencing diarrhea after taking this supplement it may not be related at all! Additionally, some research has shown that cannabis has an anti-diarrheal effect in some cases so keep this in mind if you experience diarrhea after taking it for the first time!

CBD is known to cause drowsiness and sleepiness. It can also interact with other medications you’re taking, like blood thinners. In high doses, CBD can cause liver damage. Some people also experience dry mouth, low blood pressure, and lightheadedness. CBD can also affect your appetite. If you’re thinking about using CBD, be sure to talk to your doctor first.

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Final Thoughts

Despite the need for more research, it seems generally safe to combine CBD with Viagra. You should always see your doctor before taking any medicine, including natural ones like CBD, as it might slow the metabolism and occasionally raise the chance of Viagra’s adverse effects.

Start with a modest dose and gradually raise it as needed because combining the two substances may intensify their effects. Always be sure to get top-notch products from reputable suppliers.

How to use CBD oil for erectile dysfunction

If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.

Erectile dysfunction or ED is a hot topic, and many people are confused about what the issue entails and which remedies—if any—actually work. One popular, albeit controversial, treatment strategy involves using cannabidiol, aka CBD, a molecule found in hemp and marijuana that doesn’t make you feel high but may offer other benefits.

Read on to learn whether CBD oil for erectile dysfunction or sexual performance anxiety works and how to use it.

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How does CBD for erectile dysfunction work?

Unlike THC, CBD doesn’t appear to alter consciousness or cause a person to feel “high.” Currently, it is only FDA-approved to help treat seizure disorders. However, there is ongoing research into the potential benefits of CBD for anxiety, chronic pain, and other health conditions. CBD may also have anti-inflammatory and anti-cancer properties, but these are still being studied (Meissner, 2022).

Scientists don’t fully understand how CBD works, but they suspect it affects certain brain chemicals. Cannabinoids like CBD work by interacting with the body’s endocannabinoid system (ECS). This system involves the whole body and may play a role in pain, memory, movement, appetite, metabolism, and immune system function (Sheikh, 2022).

Here are four ways CBD oil may help with erectile dysfunction:

1. Could lower general anxiety and stress

Some research suggests that CBD may benefit people with anxiety disorders and brain diseases like Alzheimer’s and Parkinson’s (Meissner, 2022). Anxiety can sometimes affect sexual performance and sex drive, so if CBD is beneficial for anxiety disorders, it may help with ED too.

Researchers have found that CBD works on serotonin receptors in the brain. Serotonin can affect a person’s anxiety and fear levels, which is why CBD could lower general stress and anxiety levels (Blessing, 2015).

2. May decrease performance anxiety

Sexual performance anxiety can be caused by relationship problems, a negative body image, fear of disappointing your partner, or pressure to have an orgasm. Since CBD may help lower anxiety levels, it could, in turn, decrease performance anxiety (Blessing, 2015).

According to a variety of studies and preclinical evidence, CBD shows promise to help people with:

If a person’s performance anxiety stems from any of those issues, the studies suggest CBD could help (Blessing, 2015).

What is an erection, and how does it work?

3. Could lower blood pressure

CBD has the potential to lower blood pressure in people with increased heart rates, according to one study from 2017 (Jadoon, 2017).

When blood pressure is lower, it can improve circulation, which may allow more blood to flow to the penis.

4. May improve sleep

Lack of sleep can wreak havoc on the body. If you’re not getting enough rest, it could contribute to erectile dysfunction (Cho, 2018).

Anxiety and stress can often cause sleep disturbances, which is why CBD could help you get a good night’s rest. Some studies suggest that CBD may have therapeutic potential for insomnia (Babson, 2017). In a different study of 72 adults with either anxiety, poor sleep, or both, sleep scores improved with CBD use for 66.7% of the participants (Shannon, 2019).

If a lack of sleep is causing your ED, using CBD for sleep could be helpful.

Can CBD help with ED?

While there’s not a ton of research on the topic of CBD as a treatment for ED, one study found that there are ECS receptors involved in male fertility. And while some studies suggest that cannabis may be indirectly associated with erectile dysfunction and may cause ED in young habitual cannabis users, more research on CBD is needed (du Plessis, 2015).

Some research has shown that CBD may help reduce anxiety for some people (Shannon, 2019). Because anxiety may play a significant role in erectile dysfunction or even cause erectile dysfunction, CBD oil for erectile dysfunction may be a helpful tool. However, more research is needed in this area.

CBD for anxiety: dosage, benefits and side effects

How to use CBD oil for ED

How to use CBD oil will depend on the form you have. You can swallow liquid oils or put them under your tongue and let them absorb that way. You can swallow pills or capsules the same way you would other medications. You may need a special vaporizer or inhaler to use the vaporized forms.

CBD oil comes in many forms, including (Bruni, 2018):

  • Liquid oils
  • Pills or capsules
  • Liquid oils that you swallow or edibles
  • Chewing gum
  • CBD inhaler
  • Creams

You can use CBD for ED by incorporating one or more of these CBD products into your daily routine. Keep in mind that CBD isn’t a magic fix for ED. You’ll want to experiment with different products to see what works best for you. Eating a gummy or taking a CBD capsule may produce quicker results. However, it varies from person to person and depends on the CBD dosage, type, and other factors.

Dosage

The FDA doesn’t approve most CBD products, so accurate dosage guidelines are hard to come by.

The drug, Epidiolex, is a CBD-based treatment used for seizures associated with Lennox-Gastaut syndrome. It’s recommended that people start at a dose of 5 milligrams per kilogram of body weight per day (mg/kg/day). After one week, users can increase their dose to 20 mg/kg/day, depending on their reaction to the drug (DailyMed, 2022).

If you don’t know how much CBD to take, start with a low dose, and work your way up from there over time.

Potential risks or considerations of taking CBD

If you’re considering taking CBD in an attempt to treat erectile dysfunction or any other medical condition or health issue, it’s important to understand the potential risks involved. The US Food and Drug Administration (FDA) has approved one cannabis-derived and three cannabis-related drug products, all of which require a prescription (FDA-a, 2020):

  • Epidiolex for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex (DailyMed, 2022)
  • Syndros and Marinol for the treatment of anorexia associated with weight loss in people with AIDS and nausea/vomiting in people receiving cancer chemotherapy (FDA, 2017; DailyMed-a, 2021)
  • Cesamet for the treatment of nausea/vomiting in people receiving cancer chemotherapy (DailyMed-b, 2021)

Because the FDA doesn’t generally regulate CBD products, it can be difficult to determine the quality of the products you’re getting. It can also be difficult to know what form of CBD (i.e., CBD oil, gummies, CBD capsules, etc.) may work best for you.

Using any drug without this knowledge can cause a host of unwanted side effects that are difficult to predict without guidance or regulation.

Is erectile dysfunction reversible? In most cases, it’s treatable

Potential CBD side effects

CBD side effects may vary from person to person. A few possible side effects include (FDA-b, 2020):

Other benefits of CBD

CBD has plenty of potential benefits, and they’re not all specifically for ED. Some of these benefits include:

  • Pain relief
  • Mental health and wellness assistance
  • Performance anxiety
  • Improved sleep
  • Anti-inflammatory properties
  • Antioxidant properties
  • Anti-nausea

While there are no studies explicitly demonstrating the benefits of CBD on ED, there are studies that indicate CBD may be helpful in the treatment of other conditions. Evidence suggests CBD could be a beneficial treatment for multiple anxiety disorders, but additional research is needed (Shannon, 2019).

Researchers also believe CBD may help slow down messages sent to the brain, change calcium levels in brain cells, and decrease brain inflammation, all of which may help prevent seizures (Maroon, 2018).

Animal studies indicate other potential benefits of CBD, such as its anti-inflammatory potential to treat arthritis pain. But more research is necessary to understand how these benefits could translate to humans (Hammell, 2016).

6 best CBD gummies for anxiety

What causes erectile dysfunction?

Erectile dysfunction can have many causes. Some of these include (NIH, 2017):

Other treatment options for ED

CBD may not be an approved treatment for ED, but there are several other treatment options available.

Medication

After lifestyle modifications, the first line of treatment for ED is usually oral medications taken before sexual intercourse. These drugs are known as PDE-5 inhibitors, and the most common one is sildenafil (brand name Viagra; see Important Safety Information). Other PDE-5 inhibitors include (Krzastek, 2019):

  • Tadalafil (brand name Cialis; see Important Safety Information)
  • Vardenafil (brand name Levitra)
  • Avanafil (brand name Stendra)

Lifestyle changes

Certain lifestyle changes and improvements can also have a positive effect on ED. The following lifestyle habits have all been shown to contribute to ED (NIH, 2017):

  • Lack of physical activity
  • An unhealthy, unbalanced diet
  • Cigarette smoking

Taking actions to modify these behaviors and health conditions may have a major impact.

What is horny goat weed? Does it work?

Managing underlying health conditions

Certain health conditions could cause ED. Some of these include (Krzastek, 2019):

Natural supplements

There are also some natural supplements, herbs, and vitamins that may or may not benefit ED. Some of these include:

  • Horny goat weed: A traditional Chinese medicinal herb often used to treat fatigue and low sex drive. Animal and lab studies have shown that horny goat weed contains a substance called icariin, a mild PDE-5 inhibitor, but it’s unclear if these benefits translate to humans (Anand Ganapathy, 2021).
  • Yohimbine: Some research suggests that Yohimbine, the active ingredient in yohimbe bark, may work better than a placebo to treat ED (NIH, 2020).
  • Vitamin D:Vitamin D deficiency may contribute to problems with erections.
  • Vitamin B3: Some research has shown vitamin B3 supplementation may help increase penile blood flow (Crafa, 2020).
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In general, research on vitamins and natural supplements is limited, so it’s best to work with your healthcare professional to treat ED.

What is CBD?

CBD, or cannabidiol, is a natural substance called a cannabinoid. It comes from the cannabis plant, which is part of the Cannabaceae family. CBD is one of two main cannabinoids; the other one is delta-9-tetrahydrocannabinol (THC).

Cannabis plants with higher levels of THC are classified as marijuana and are controlled substances (FDA-b, 2020). Cannabis plants with very low THC are classified as hemp. CBD can be found in both marijuana and hemp.

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What is erectile dysfunction?

ED is when a person cannot get or sustain an erection long enough to have sex.

Can you naturally cure erectile dysfunction?

There are natural remedies for ED such as CBD, horny goat weed, vitamin D, and vitamin B3. However, there is not enough evidence to say that these natural methods will cure ED.

How do you use CBD for sex?

You can take CBD in a variety of forms, such as tinctures, gummies, and liquids. Taking CBD before sex could help reduce anxiety, which may be causing your ED. CBD could also help increase blood flow to the penis by potentially lowering blood pressure.

Does CBD help with arousal?

CBD could help with arousal by lowering anxiety and stress levels, which can help you relax.

References

  1. Anand Ganapathy, A., Hari Priya, V. M., & Kumaran, A. (2021). Medicinal plants as a potential source of phosphodiesterase-5 inhibitors: a review. Journal of Ethnopharmacology, 267, 113536. doi:10.1016/j.jep.2020.113536. Retrieved from https://pubmed.ncbi.nlm.nih.gov/33137431/
  2. Babson, K. A., Sottile J., & Morabito, D. (2017). Cannabis, cannabinoids, and sleep: a teview of the literature. Current Psychiatry Reports (4), 23. doi:10.1007/s11920-017-0775-9. Retrieved from https://pubmed.ncbi.nlm.nih.gov/28349316/
  3. Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(14), 825-836. doi: 10.1007/s13311-015-0387-1. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/
  4. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., et al. (2018). Cannabinoid delivery systems for pain and inflammation treatment. Molecules(Basel, Switzerland), 23(10), 2478. doi:10.3390/molecules23102478. Retrieved from https://pubmed.ncbi.nlm.nih.gov/30262735/
  5. Cho J. W. & Duffy, J. F. (2018). Sleep, sleep disorders, and sexual dysfunction. World Journal of Men’s Health. 37(3), 261-275. doi:10.5534/wjmh.180045. Retrieved from https://pubmed.ncbi.nlm.nih.gov/30209897/
  6. Crafa, A., Cannarella, R., Condorelli, R. A., et al. (2020). Is there an association between vitamin d deficiency and erectile dysfunction? A systematic review and meta-analysis. Nutrients, 12(5), 1411. doi:10.3390/nu12051411. Retrieved from https://pubmed.ncbi.nlm.nih.gov/32422943/
  7. DailyMed-b. (2021). Cesamet- nabilone capsule. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83c7ac15-ece9-47de-b83c-d575544fa449
  8. DailyMed. (2022). Epidiolex- cannabidiol solution. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8bf27097-4870-43fb-94f0-f3d0871d1eec
  9. DailyMed-a. (2021). Syndros- dronabinol solution. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a7801c70-995d-46a2-91ee-141ef427c6b5
  10. du Plessis, S. S., Agarwal, A., & Syriac, A. (2015). Marijuana, phytocannabinoids, the endocannabinoid system, and male fertility. Journal of Assisted Reproduction and Genetics, 32(11), 1575–1588. doi:10.1007/s10815-015-0553-8. Retrieved from https://pubmed.ncbi.nlm.nih.gov/26277482/
  11. Hammell, D. C., Zhang, L. P., Ma, F., et al. (2016). Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. European Journal of Pain(London, England), 20(6), 936–948. doi:10.1002/ejp.818. Retrieved from https://pubmed.ncbi.nlm.nih.gov/26517407/
  12. He, C., Wang, Z., & Shi, J. (2020). Pharmacological effects of icariin. Advances in Pharmacology(San Diego, Calif.), 87, 179–203. doi:10.1016/bs.apha.2019.10.004. Retrieved from https://pubmed.ncbi.nlm.nih.gov/32089233/
  13. Jadoon, K. A., Tan, G. D., & O’Sullivan, S. E. (2017). A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI Insight; 2(12), e93760. doi:0.1172/jci.insight.93760. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470879/
  14. Krzastek, S. C., Bopp, J., Smith, R. P., & Kovac, J. R. (2019). Recent advances in the understanding and management of erectile dysfunction. F1000Research, 8, F1000 Faculty Rev-102. doi:10.12688/f1000research.16576.1. Retrieved from https://pubmed.ncbi.nlm.nih.gov/30740217/
  15. Maroon, J. & Bost, J. (2018). Review of the neurological benefits of phytocannabinoids. Surgical Neurology International, 9, 91. doi:10.4103/sni.sni_45_18. Retrieved from https://pubmed.ncbi.nlm.nih.gov/29770251/
  16. Meissner, H. & Cascella, M. (2022). Cannabidiol (CBD). StatPearls. Retrieved on Aug. 12, 2022 from https://www.ncbi.nlm.nih.gov/books/NBK556048/
  17. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). (2017). Symptoms & Causes of Erectile Dysfunction. Retrieved from https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction/symptoms-causes
  18. National Institute of Diabetes and Digestive and Kidney Diseases (NIH). (2020). Yohimbine. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK548703/
  19. Ng, C. F., Lee, C. P., Ho, A. L., & Lee, V. W. (2011). Effect of niacin on erectile function in men suffering erectile dysfunction and dyslipidemia. The Journal of Sexual Medicine, 8(10), 2883–2893. doi:10.1111/j.1743-6109.2011.02414.x. Retrieved from https://pubmed.ncbi.nlm.nih.gov/21810191/
  20. Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in anxiety and sleep: A large case series. The Permanente Journal, 23, 18–041. doi: 10.7812/TPP/18-041. Retrieved from https://pubmed.ncbi.nlm.nih.gov/30624194/
  21. Sheikh, N. K. & Dua, A. (2022). Cannabinoids. StatPearls. Retrieved on Aug. 12, 2022 from https://www.ncbi.nlm.nih.gov/books/NBK556062/
  22. Sooriyamoorthy, T. & Leslie, S. W. (2021). Erectile dysfunction. StatPearls. Retrieved on Aug. 12, 2022 from https://www.ncbi.nlm.nih.gov/books/NBK562253/
  23. U.S. Food and Drug Administration (FDA-a). (2020). FDA and cannabis: research and drug approval process. Retrieved on Aug 12, 2022 from https://www.fda.gov/news-events/public-health-focus/fda-and-cannabis-research-and-drug-approval-process
  24. U.S. Food and Drug Administration (FDA). (2017). Marinol: highlights of prescribing information. Retrieved on Aug 12, 2022 from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018651s029lbl.pdf
  25. U.S. Food and Drug Administration (FDA-b). (2020). What you need to know (and what we’re working to find out) about products containing cannabis or cannabis-derived compounds, Including CBD. Retrieved on Aug 12, 2022 from https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis

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Important Safety Information for Sildenafil (Viagra)

What are the most important things I need to know about VIAGRA® (sildenafil citrate) 25 mg, 50 mg, and 100 mg tablets and generic VIAGRA®?

Discuss your health with your doctor to ensure that you are healthy enough for sex. If you experience chest pain, dizziness, or nausea during sex, seek immediate emergency medical attention.

  • VIAGRA® and generic VIAGRA® can cause serious side effects. Serious, but rare, side effects include:
    • an erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, seek emergency medical attention right away. If it is not treated right away, priapism can permanently damage your penis.
    • sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking VIAGRA and call your healthcare provider right away if you have any sudden vision loss
    • sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you have these symptoms, stop taking VIAGRA and contact a doctor right away

    Who should not take VIAGRA® or generic VIAGRA®?

    Do not take VIAGRA® or generic VIAGRA® if you:

    • Take any medicines called nitrates, often prescribed for chest pain, or guanylate cyclase stimulators like Adempas (riociguat) for pulmonary hypertension. Your blood pressure could drop to an unsafe level
    • Are allergic to sildenafil, as contained in VIAGRA® and REVATIO®, or any of the ingredients in VIAGRA® or generic VIAGRA® tablets.
    • Are a women or a child

    When should I call my primary provider?

    Call your primary provider right away if you:

    • Have an erection that lasts longer than 4 hours
    • Experience a sudden loss of vision in one or both eyes
    • Experience a sudden decrease in or loss of hearing
    • Experience chest pain, dizziness, or nausea during sex
    • Take too much Viagra or sildenafil citrate

    If you are experiencing a medical emergency, call 911 or seek immediate medical attention.

    What are the most common side effects of VIAGRA® and generic VIAGRA®?

    The most common side effects are:

    • headache
    • flushing
    • upset stomach
    • abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision
    • stuffy or runny nose
    • back pain
    • muscle pain
    • nausea
    • dizziness
    • rash

    What should I tell my Roman-affiliated provider before taking VIAGRA® and generic VIAGRA®?

    Before you take VIAGRA® or generic VIAGRA® , tell your healthcare provider if you:

    • Have or have had heart problems such as a heart attack,irregular heartbeat, angina, chest pain, narrowing of the aortic valve, or heart failure
    • Have had heart surgery within the last 6 months
    • Have pulmonary hypertension
    • Have had a stroke
    • Have low blood pressure, or high blood pressure that is not controlled
    • Have a deformed penis shape
    • Have had an erection that lasted for more than 4 hours
    • Have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia
    • Have retinitis pigmentosa, a rare genetic (runs in families) eye disease
    • Have ever had severe vision loss, including an eye problem called NAION
    • Have bleeding problems
    • Have or have had stomach or intestinal ulcers
    • Have liver problems
    • Have kidney problems or are having kidney dialysis
    • Have any other medical conditions

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

    VIAGRA may affect the way other medicines work, and other medicines may affect the way VIAGRA works, causing side effects.

    Especially tell your healthcare provider if you take any of the following:

    • Medicines called nitrates
    • Medicines called guanylate cyclase stimulators such as Adempas® (riociguat)
    • Medicines called alpha-blockers such as Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl), Uroxatral® (alfuzosin HCl), Jalyn® (dutasteride and tamsulosin HCl), or Rapaflo® (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients, the use of VIAGRA® with alpha-blockers can lead to a drop in blood pressure or to fainting
    • Medicines called HIV protease inhibitors, such as ritonavir (Norvir®), indinavir sulfate (Crixivan®), saquinavir (Fortovase® or Invirase®), or atazanavir sulfate (Reyataz®)
    • Oral antifungal medicines, such as ketoconazole (Nizoral®) and itraconazole (Sporanox®)
    • Antibiotics, such as clarithromycin (Biaxin®), telithromycin (Ketek®), or erythromycin
    • Other medicines that treat high blood pressure
    • Other medicines or treatments for ED
    • VIAGRA® contains sildenafil, which is the same medicine found in another drug called REVATIO®. REVATIO® is used to treat a rare disease called pulmonary arterial hypertension (PAH). VIAGRA® should not be used with REVATIO® or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such as Adcirca [tadalafil])

    Withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.

    What is the FDA-approved use of VIAGRA® and generic VIAGRA®?

    VIAGRA® (sildenafil citrate) is prescription medicine used to treat erectile dysfunction (ED).

    Roman-affiliated doctors may prescribe VIAGRA® or generic VIAGRA® for the treatment of premature ejaculation (PE), if they believe in their medical judgment that it is an appropriate course of treatment. While this is not an FDA-approved use of the drug, the American Urological Association has included the use of sildenafil citrate in the treatment of PE in its Guideline on the Pharmacologic Management of Premature Ejaculation.

    You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

    Please see the full Prescribing Information for complete safety information.

    Product names referenced herein are trademarks of their respective owners.

    Important Safety Information for Tadalafil (Cialis)

    What Is The Most Important Information I Should Know About CIALIS® (tadalafil) and generic CIALIS®?

    • CIALIS® and generic CIALIS® can cause serious side effects. Serious, but rare, side effects include:
      • An erection that won’t go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis, including the inability to have erections.
      • Changes in vision. Color vision changes, such as seeing a blue tinge (shade) to objects or having difficulty telling the difference between the colors blue and green.
      • Sudden decrease or loss of vision. In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including CIALIS® and generic CIALIS®) reported a sudden decrease or loss of vision in one or both eyes. It is uncertain whether PDE5 inhibitors directly cause the vision loss. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including CIALIS® and generic CIALIS®, and call a healthcare provider right away.
      • Sudden loss or decrease in hearing. Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including CIALIS® and generic CIALIS®. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience these symptoms, stop taking CIALIS® and generic CIALIS® and contact a healthcare provider right away.
      • ED is a condition where the penis does not fill with enough blood to harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his healthcare provider for help if the condition bothers him.
      • CIALIS® and generic CIALIS® help increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away. Some form of sexual stimulation is needed for an erection to happen with CIALIS® or generic CIALIS®.
      • CIALIS® and generic CIALIS® do not:
        • Cure ED
        • Increase a man’s sexual desire
        • Protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your healthcare provider about ways to guard against sexually transmitted diseases.
        • Serve as a male form of birth control
        • Take CIALIS® or generic CIALIS® exactly as your healthcare provider prescribes it. Your healthcare provider will prescribe the dose that is right for you. Do not change your dose or the way you take CIALIS® or generic CIALIS® without talking to your healthcare provider.

        Who Should Not Take CIALIS® or generic CIALIS®?

        Do not take CIALIS® or generic CIALIS® if you:

        • Have severe liver disease. Tell your doctor if you have mild to moderate liver disease as you may need dosage reductions.
        • Have severe kidney disease. Tell your doctor if you have mild to moderate kidney disease as you may need dosage reductions
        • Take any medicines called “nitrates”
        • Use recreational drugs called “poppers” like amyl nitrite and butyl nitrite
        • Take any medicines called guanylate cyclase stimulators, such as riociguat
        • Are allergic to CIALIS®, tadalafil or ADCIRCA®, or any of its ingredients

        When should I call my primary provider?

        Call your primary provider right away if you:

        • Have an erection that lasts longer than 4 hours
        • Experience a sudden loss of vision in one or both of your eyes
        • Experience a sudden decrease or loss hearing
        • Take too much CIALIS® or generic CIALIS®
        • Have an allergic reaction to CIALIS® or generic CIALIS®
        • Symptoms of an allergic reaction may include:
        • Rash
        • Hives
        • Swelling of the lips, tongue, or throat
        • Difficulty breathing or swallowing

        Call your healthcare provider or get help right away if you have any of the symptoms of an allergic reaction listed above.

        If you are experiencing a medical emergency, call 911 or seek immediate medical attention.

        What Should I Tell My Roman-affiliated Provider Before Taking CIALIS® and generic CIALIS®?

        Tell your Roman-affiliated provider about all your medical problems, including if you:

        • Have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your healthcare provider if it is safe for you to have sexual activity. You should not take CIALIS® and generic CIALIS® if your healthcare provider has told you not to have sexual activity because of your health problems.
        • Have pulmonary hypertension
        • Have low blood pressure or have high blood pressure that is not controlled
        • Have had a stroke
        • Have liver problems
        • Have kidney problems or require dialysis
        • Have retinitis pigmentosa, a rare genetic (runs in families) eye disease
        • Have ever had severe vision loss, including a condition called NAION
        • Have stomach or intestinal ulcers
        • Have a bleeding problem
        • Have a deformed penis shape or Peyronie’s disease
        • Have had an erection that lasted more than 4 hours
        • Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia

        Tell your healthcare provider about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

        Especially tell your healthcare provider if you take any of the following:

        • Medicines called nitrates
        • Medicines called guanylate cyclase stimulators, such as riociguat (Adempas®), used to treat pulmonary hypertension
        • Medicines called alpha blockers. These include Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl), Uroxatral® (alfuzosin HCl), 4 Jalyn® (dutasteride and tamsulosin HCl) or Rapaflo® (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. If CIALIS® or generic CIALIS® is taken with certain alpha blockers, your blood pressure could suddenly drop. You could get dizzy or faint.
        • Other medicines to treat high blood pressure (hypertension)
        • Medicines called HIV protease inhibitors, such as ritonavir (Norvir® , Kaletra® )
        • Oral antifungals such as ketoconazole (Nizoral® ), itraconazole (Sporanox® )
        • Antibiotics such as clarithromycin (Biaxin® ), telithromycin (Ketek® ), erythromycin (several brand names exist. Please consult your healthcare provider to determine if you are taking this medicine).
        • Other medicines or treatments for ED.
        • Tadalafil is also marketed as ADCIRCA® for the treatment of pulmonary arterial hypertension. Do not take both CIALIS® or generic CIALIS® and ADCIRCA®. Do not take sildenafil citrate (Revatio®, Viagra®) with CIALIS® or generic CIALIS®.

        Withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.

        What are the most common side effects of CIALIS® or generic CIALIS®?

        The most common side effects with CIALIS® and generic CIALIS® are:

        • Headache
        • Indigestion
        • Back pain
        • Muscle aches
        • Flushing
        • Stuffy or runny nose

        What is the FDA-approved Use of CIALIS® and generic CIALIS®?

        CIALIS® and generic CIALIS® are prescription medicines used to treat erectile dysfunction (ED), symptoms of benign prostatic hyperplasia (BPH), or both.

        Roman-affiliated doctors may prescribe CIALIS® for the treatment of premature ejaculation (PE), if they believe in their medical judgment that it is an appropriate course of treatment.

        You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

        Please see the full Prescribing Information for complete safety information.

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