Everything you need to know about CBD oil for dogs with seizures and help finding an effective product and dosage for your dog. The best CBD oil for dog seizures contains the full spectrum of cannabinoids and terpenes, and offers higher dosages per serving. Here we highlight the most trustworthy brands. If your dog gets seizures, you’ll do anything you can to help him. Find out about the benefits of CBD oil for dogs with seizures …
CBD Oil for Dog Seizures
It’s no exaggeration to say CBD has transformed my life. It helped my own health, and it helped my dog, Biscuit, who suffered from arthritis, live out the rest of her long life as comfortably and actively as possible. Not only has CBD helped me, my pet, and the pets of my family and friends, CBD has shown a light of hope into the lives of thousands of other pet parents.
Studies on CBD have been shown it to help animals with so many ailments, including anxiety, pain, and seizures. I read a new study practically everyday expounding on the myriad benefits of it. In my journey to learning more about the natural wonders of CBD, I’ve educated my followers along the way, letting them know that CBD has legitimate and proven uses. In turn, my customers send me testimonials that keep me going every day.
Testimonials like those from Darlene about her dog Myrna. I personally spoke to Darlene on the phone about whether or not CBD oil would help her dog, and I’m glad she gave it a go, because thanks to CBD, Myrna is now living the life she was meant to. Below, you can read Darlene’s full testimonial about Myrna and also the full background on CBD oil for dogs, including why and how it works.
CBD For Seizures – Myrna’s Story
“My poodle Myrna [pictured above] suddenly started experiencing seizures when she was about 5 years old. Up to that point, she’d been a funny, smart dog that would regularly take her leash in her mouth and dance up to me and as if she was saying, ‘hey, I have a fun idea, let’s go for a walk!”
“To tell you the fear and anxiety I felt when watching my baby seize for the first time is something I don’t even want to fully describe. But it must have been worse for her. The look in her eyes and her anxious panting spoke volumes that she couldn’t say. I rushed her to the vet who took a ‘wait and see’ approach. Soon after, she experienced more seizures and the vet prescribed phenobarbital. Which seemed to help, but also seemed to change Myrna into a lethargic couch potato. I wanted Myrna to be herself and ALSO not to have seizures. That’s when I started looking for natural, holistic alternatives and found Relievet CBD Oil.”
“I started cautiously dosing her and with my vet’s supervision, weaning her down on phenobarbital. Now she’s on a low dose of phenobarbital and a good dose of CBD and she hasn’t had any seizures in months! But more importantly, thanks to the natural medicine of CBD she’s herself again. Back to her old tricks, bringing me her leash and toys to tell me it’s time to go on a walk or time to play. I’m glad I chose Relievet to help my baby because they helped me every step of the way with any questions I had. The relief I have over not worrying over Myrna makes me so happy I chose to try the natural approach.”
Best CBD Oils for Dogs With Seizures & Epilepsy (2022)
Dogs can suffer from seizures due to a variety of reasons, from underlying health conditions to toxins.
CBD oil has been shown as one of the best natural remedies for dog seizures and related symptoms — making it a viable alternative to conventional prescription drugs.
In this article, we shed light on the best CBD oils for dog seizures, explain how CBD may help your canine friend, and how to ensure a well-informed purchase.
CBD & Dog Seizures (Highlights)
- Seizures are sudden changes in behavior caused by abnormal electrical activity in the brain. They can occur as trembling, twitching, confusion, drooling, loss of balance or consciousness, involuntary urination, and convulsions.
- Dogs may seize due to food poisoning, diseases like distemper, liver disease, kidney failure, brain injury, cancer, a stroke, or a hereditary disease such as epilepsy.
- Conventional medications may provide short-term relief from dog seizures, but they come with unpleasant side effects, such as headaches, irritation, hypersensitivity, nausea, vomiting, and sedation.
- CBD is one of the two major cannabinoids from cannabis plants. It’s non-intoxicating, so it won’t get your dog high. It can, however, help with the management of a wide range of symptoms and health conditions, including seizures.
- By interacting with the endocannabinoid system (ECS), CBD reaches specific receptors in the brain and dampens the activity of the nervous system – reducing the frequency and intensity of dog seizures.
- In one clinical trial, 89% of dogs that received CBD had a reduction in the frequency of seizures. The research team concluded the results were significant and promising for future research.
- Consult your veterinarian before giving your dog CBD oil for seizures. CBD interacts with at least 60% of prescribed medications, so a consultation with a vet will help you avoid the risk of cross-side effects resulting from those interactions.
Best CBD Oil for Dog Seizures
1. Royal CBD
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
- Non-GMO, pesticide-free hemp from Colorado
- CO2 extraction
- Full-spectrum CBD
- Up to 500 mg per bottle
- Bacon flavor
- Third-party tested for potency and purity
- Limited flavor options
- Not available in local stores (yet)
Royal CBD is a premium brand that uses the same premium-quality CBD extracts in its line for pets as it does in its collection for humans — ensuring the highest safety and efficacy.
These CBD pet oils are considered one of the best CBD oil for dogs which contain the full spectrum of cannabinoids and terpenes, leveraging the entourage effect in hemp and increasing CBD’s efficacy overall.
You can choose from two potencies: 250 mg (small and medium dogs) and 500 mg (large dogs).
The oil is suspended in organic MCT oil that boosts its absorption and ‘dilutes’ the hempy flavor.
Speaking of which, if your buddy dislikes the taste of unflavored CBD oil, the bacon-flavored version will change its mind in the nick of time.
All Royal CBD products are triple-tested in an ISO-certified laboratory, with complete results for the potency of CBD, the entire cannabinoid and terpene profile, and contaminants like pesticides, heavy metals, solvents, and mold.
2. Gold Bee
- Organic hemp
- Supercritical CO2 extraction
- Full-spectrum CBD
- 600 mg per bottle
- Batch-specific lab reports
- Only one strength is available
- It can be difficult to dose in smaller dogs
Gold Bee is a company founded by people with remarkable expertise in the superfoods industry. Its products are made in one facility and in small batches, ensuring top-shelf quality.
Gold Bee offers all-organic products for dogs, such as full-spectrum CBD oil and CBD Goofy Bones (treats). Look for these products in CBD stores for dogs near you.
The oil contains 600 mg of full-spectrum CBD, sourced from organic, terpene-rich hemp strains that Gold Bee grows in collaboration with local farmers. It comes in a delish peanut butter flavor.
At 20 mg of CBD per mL, this oil is a great pick for larger dogs and those whose seizures require high doses of CBD daily. You can also give it to a medium-sized dog and benefit from longer-lasting supplies.
However, when it comes to small breeds like Schnauzers or Chihuahuas, we recommend the low-potency option from Royal CBD.
Does CBD Oil Help Dogs With Seizures?
Yes, a few studies — including one clinical trial — as well as anecdotal evidence from dog parents indicate that CBD can help with dog seizures.
CBD targets specific receptors in the brain (TRPV1 and GPR55) to prevent excessive activity in the central nervous system.
It also helps raise GABA levels — another inhibitory neurotransmitter.
The above mechanisms answer why CBD appears to help where conventional seizure medications fail to produce the desired results.
In fact, CBD became popular worldwide because of a young girl Charlotte Figi whose parents used CBD to reduce the frequency and severity of human epileptic seizures with great success.
CBD stands out from other health supplements thanks to its versatility. Not only can it help with dog seizures, but it also aids in reducing anxiety, joint pain, digestive problems, inflammation, and loss of appetite.
Here we explain what makes CBD so special.
How CBD Works to Reduce Seizures in Dogs
The anti-epileptic mechanism of CBD in dogs stems from its interaction with the endocannabinoid system (ECS).
The ECS is a complex neurochemical network made of neurotransmitters (endocannabinoids), receptors, and enzymes. Together, these components create the master regulatory system in all mammals that promotes and helps maintain homeostasis throughout the body.
CBD and Cannabinoid Receptors
CBD indirectly acts on the activity of CB1 receptors in the brain. It also binds to CB2 receptors, whose highest concentrations can be found in the immune system and peripheral organs.
Seizures are bursts of uncontrolled activity between the nerve cells. It leads to disrupting the distribution of signals and inflicts inflammation upon neurons.
Studies have found that ECS and epilepsy are closely linked together. CBD has been highlighted by researchers as a potential anticonvulsant, anti-inflammatory, and neuroprotectant.
Hence its potential to treat epilepsy in dogs.
Is CBD the Only Anti-epileptic Cannabinoid?
CBD oil contains more than 400 chemical compounds. Another anti-epileptic cannabinoid is CBDV (cannabidivarin). Both cannabinoids interact with the TRPV1 receptor.
This receptor mostly occurs in the brain’s hippocampus region. It controls many cognitive processes, such as memory, learning, and decision making — but it’s also associated with seizure activities.
One theory proposes that CBD and CBDV can prevent epilepsy by blocking the overexcitement of this receptor.
In a similar fashion, CBD can modulate the activity of neurons by acting on other seizure-related receptors, such as G-protein-coupled receptor-55 (GPR55) and the equilibrative nucleoside transporter 1 (ENT-1).
Studies on CBD and Dog Seizures
- A 2019 study published in the journal Molecules concluded that CBD is a potentially effective remedy for epilepsy, and it comes without the side effects of conventional anti-epileptics.
- A 2017 study compared the anticonvulsant effects of CBD and CBD. The authors concluded that CBD has a stronger anticonvulsant profile than THC.
- In another 2021 study, the researchers found that CBD enhanced the efficacy of clobazam, a common pharmaceutical anticonvulsant.
What Are Clinical Trials Saying About the Efficacy of CBD Oil for Dog Seizures?
CBD shows significant potential as a treatment for dogs with seizures. The AKC Canine Health Foundation (AKC HF) has recently run a clinical trial that analyzed the efficacy of CBD oil for dogs with epilepsy.
This was the first study that used whole-plant CBD oil instead of synthetic cannabidiol.
The experiment was conducted by two important scientists in the veterinary space – Stephanie McGrath, a veterinary neurologist at Colorado State University, and Diane Brown, the CEO of the AKCC HF.
The study started by administering CBD oil to nine dogs and a placebo to seven others in laboratory conditions. Neither the owners nor the scientists knew which substances each dog took.
The team monitored the dogs with seizures for the next three months. Once the trial ended, the dogs went through a 4-week washout period. At the end of the study, each dog received whichever substance they didn’t get the first time for the same time.
As reported by Science Daily, 89% of dogs in this study experienced a significant reduction in the severity and frequency of seizures. The result was statistically significant, showing great promise for parents who want to use CBD oil to treat epilepsy in their four-legged friend.
How to Give Dogs CBD Oil for Seizures
Consistency is critical if you want to achieve the best results with CBD and significantly reduce seizures in your dog.
You need to administer it regularly.
Not just during a seizure attack but every single day.
CBD modulates and helps optimize your dog’s ECS, so if the seizures stem from a clinical endocannabinoid deficiency, you can use CBD and other cannabinoids in CBD oil to regulate the activity of brain cells.
This makes CBD a potential preventive option when it comes to dog seizures.
How Long Does It Take for CBD to Work for Dog Seizures?
The acute effects of CBD oil on the nervous system can take anywhere from a few minutes to half an hour to take hold. However, for effective seizure management, you may need to show more patience — for up to two weeks.
If you do not see any results, increase the dosage and continue for around 5 days. Repeat until you find the optimal amount of CBD for your dog.
CBD and Dog Seizure Medication: Can You Give Them Together?
Earlier, we mentioned that CBD could potentiate the effects of clobazam, an anticonvulsant drug used to treat epilepsy.
That’s because CBD interacts with a broad range of pharmaceutical medications.
CBD is a potent inhibitor of the CYP450 enzyme system — a set of enzymes that metabolize the majority of drugs in the liver. When it interacts with a drug, it can increase or decrease its levels in the bloodstream.
When you use high doses of both substances together, CBD could potentially lead to a dangerous buildup of the drug — and cause toxicity.
Sometimes, CBD may hinder the efficacy of drugs; it depends on the type of interaction in the liver.
Talk to your doctor before giving your dog CBD oil for seizures; it’s the best choice to avoid the said interactions and ensure safe supplementation.
How Much CBD Oil Should I Give My Dog for Seizures?
You’ll need to experiment most of the time.
Every dog is different, and since CBD isn’t regulated by the FDA, there is no official serving size or dosage chart for CBD for dogs when it comes to general supplementation — let alone medical conditions.
As a rule of thumb, you should follow the manufacturer’s instructions on the packaging. Start at the low end, e.g., with ¼ – ½ dropper, and see how your dog responds to that dose.
Experts recommend giving 0.25 – 0.5 mg of CBD for every pound of the dog’s weight. Obviously, a 30-pound dog will need less CBD than a 60-pound breed.
As you start adding CBD oil to the dog’s routine, slowly adjust the dosage until you find the amount that works best for its seizures, and avoid having your dog overdose with CBD oil.
Looking for more answers about seizures and how CBD oil can help? Here are the most frequently asked questions.
What are seizures?
The term ‘seizure’ refers to a sudden change in behavior caused by unusual electrical activity in the brain. They often manifest as trembling, drooling, twitching, loss of balance, convulsions, and loss of consciousness.
Although some seizures might be mild, others can last for minutes and cause issues with coordination or other health concerns for hours after the attack is over.
Most of the time, seizures indicate serious health problems such as epilepsy, organ failure, rabies, brain tumors, or liver disease.
Why do dogs seize?
10 million dogs in the United States have seizures. The causes and severity vary; a dog may seize because of diseases like liver disease, epilepsy, or kidney failure, but it may also occur as a result of food poisoning or an injury to the brain or spine.
How will I know if my dog is having seizures?
If your dog is having a seizure, it will give telltale signs, such as head or eye twitching, whimpering, whining, rapid body movements, growling, or loss of consciousness.
Seizures can be as short as a few seconds up to several minutes and may also cause involuntary urination or defecation.
What should I do when my dog has a seizure attack?
First of all, notice how long it lasts and observe any changes to your dog’s behavior once the seizure is over. If your dog doesn’t regain consciousness, take them to the vet or the nearest emergency room right away.
Other animals and people should be kept away from your seizing dog. Stay with your buddy until the seizure ends, and refrain from placing any objects or your hands in their mouth, as they may accidentally snap it. When your dog is choking, the Heimlich maneuver may come in handy.
Dogs are more likely to have another seizure after a day or two from the first one, so make sure to keep a close eye on your dog for the next 24 hours. While most dogs recover from seizures without help, some may suffer from severe side effects and require medical intervention.
Epileptic dogs usually experience more seizures than dogs with other conditions, so it’s important to monitor your dog’s behavior to notice any changes that could indicate another seizure.
What are some other medications for dogs with seizures?
- Antidepressants: amitriptyline is one of the commonly prescribed antidepressants for dog seizures because it can reduce the severity and frequency of seizures in some dogs.
- Benzodiazepines: drugs such as diazepam and midazolam can be used to relieve anxiety and panic during a seizure.
- Phenobarbital: this is a barbiturate that doctors use to manage seizures in dogs.
- Potassium bromide: also used to manage seizures, potassium bromide can be used on its own or in conjunction with phenobarbital.
- Zonisamide: Another anticonvulsant that doctors sometimes prescribe to dogs with seizures.
Do vets recommend CBD oil for dogs with seizures?
Although CBD oil isn’t a prescription drug and veterinarians can’t officially prescribe it, many vets now recommend CBD oil for dog seizures because the benefits outweigh the risk. Veterinarians often choose CBD oils as the go-to format, but in some cases, treats or a topical product may be recommended.
Can CBD oil make seizures worse?
CBD oil shouldn’t make seizures any worse. In fact, it can reduce the frequency and severity of seizures in some dogs. However, if you give your dog another medication in combination with CBD oil, such as phenobarbital or clonazepam, you should consult with a veterinarian.
If your dog receives two similarly acting compounds, it can lead to overdose symptoms, such as sedation, drowsiness, and confusion.
Can I give my dog CBD every day?
Yes, CBD is non-intoxicating, so it won’t get your dog high. It’s also non-toxic, meaning you can safely use it as a daily health supplement.
However, make sure that your CBD oil comes from organic hemp and has been extracted with CO2 to ensure maximum purity.
Speaking of which, you can easily verify the product’s purity by looking at its certificate of analysis (CoA) from a third-party laboratory.
Never trust a CBD brand that doesn’t post the lab reports on its website or, at least, send it to customers via email.
Is CBD safe for dogs?
Yes. CBD oil is a natural product with a remarkable safety profile. Even the World Health Organization (WHO) acknowledges CBD as safe and well-tolerated by humans and animals.
Key Takeaways on the Best CBD Oils for Dog Seizures
More and more dog parents are turning to CBD oil in hopes of relieving seizures in their furballs.
Unlike conventional seizure medications, CBD has a decent safety profile and uses certain neurochemical mechanisms that these drugs ignore.
Not only can CBD reduce the intensity of a seizure, but it can also prevent it by modulating the communication between neurons in your dog’s brain — bringing them to the state of homeostasis.
Always choose third-party lab-tested products that come from organic hemp, such as the brands we’ve mentioned in this article.
Check up with your veterinarian before giving your dog CBD oil for seizures; doing so will help you prevent negative interactions with other medications and gauge the most effective dosage.
- Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences, 19(3), 833. https://doi.org/10.3390/ijms19030833
- Iannotti, F. A., Hill, C. L., Leo, A., Alhusaini, A., Soubrane, C., Mazzarella, E., Russo, E., Whalley, B. J., Di Marzo, V., & Stephens, G. J. (2014). Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS chemical neuroscience, 5(11), 1131–1141. https://doi.org/10.1021/cn5000524 
- Sharir, H., & Abood, M. E. (2010). Pharmacological characterization of GPR55, a putative cannabinoid receptor. Pharmacology & therapeutics, 126(3), 301–313. https://doi.org/10.1016/j.pharmthera.2010.02.004 
- Silvestro, S., Mammana, S., Cavalli, E., Bramanti, P., & Mazzon, E. (2019). Use of Cannabidiol in the Treatment of Epilepsy: Efficacy and Security in Clinical Trials. Molecules (Basel, Switzerland), 24(8), 1459. https://doi.org/10.3390/molecules24081459 
- Perucca E. (2017). Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?. Journal of epilepsy research, 7(2), 61–76. https://doi.org/10.14581/jer.17012 
- Chuang, S. H., Westenbroek, R. E., Stella, N., & Catterall, W. A. (2021). Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome. Journal of experimental neurology, 2(2), 81–85. https://doi.org/10.33696/neurol.2.040 
- McGrath, S., Bartner, L. R., Rao, S., Packer, R. A., & Gustafson, D. L. (2019). Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional anti-epileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy. Journal of the American Veterinary Medical Association, 254(11), 1301–1308. https://doi.org/10.2460/javma.254.11.1301
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
Benefits Of CBD Oil For Dogs With Seizures
If your dog suffers from seizures, you’ve felt the stress and helplessness. So if you’ve been researching and wondering if CBD oil for dogs with seizures is a good option … I’m glad you found this post!
It’s hard to see your dog suffer and not be able to explain to him what’s happening and why.
If you’ve visited your vet already and haven’t found any answers you’re not alone. Or maybe you’re looking for an alternative to the medication the vet prescribed?
Regardless of what brought you here today, if your dog is prone to seizures, you want a way to help … and CBD oil for dogs may be just the answer you’re looking for.
And yes, it’s legal!
Seizures In Dogs
Seizures in dogs can manifest as anything from a twitch to uncontrollable shaking. They might be over quickly, or they can last for several minutes. Causes of seizures vary from dog to dog.
There are several different things that cause seizures:
- Underlying health condition like liver or kidney disease or cancer
- Electrolyte problems
- Topical flea and tick products
- Herbicides and pesticides
- Head injury
CBD Oil For Dogs With Epilepsy
If your dog suffers from regular seizures, epilepsy might be the culprit. Epilepsy means there are bursts of uncontrolled electricity in your dog’s brain. Sometimes there’s no cure for this condition, but you can manage it naturally with CBD oil.
CBD stands for Cannabidiol. It’s harvested from the cannabis hemp plant. However, unlike tetrahydrocannabinol (THC), CBD has no psychoactive properties .. so it won’t make your dog high.
This is because of the way CBD is structured. That structure affects CBD’s impact on the brain, nervous system and throughout the body.
The psychoactive effect of THC comes from the way it binds with receptors in the brain, called endocannabinoids. CBD also interacts with these endocannabinoid receptors.
Endocannabinoids are found throughout the body. The highest concentration is in the brain, spinal column, and nervous system. And it’s in these organs and systems that CBD has the greatest potential to help dogs with seizures.
CBD Oil For Seizures In Dogs
Scientists are discovering a wide variety of uses in both humans and dogs. And one of the most important uses of CBD oil for dogs is in the management of seizures. Studies as well as anecdotal evidence have shown CBD to be highly effective at managing seizures. But you don’t want to give your dog something without knowing exactly what it is and what it’s going to do.
So … how does CBD oil work?
Earlier I mentioned those endocannabinoid receptors. And they’re important when it comes to CBD oil for seizures in dogs.
There are two types of endocannabinoid receptors in your dog’s body.
- The CB2 receptors – mainly in the immune system.
- The CB1 receptors – centralized in the nervous system and the brain.
It’s these CB1 receptors that have the greatest impact on your dog’s seizure treatment. Studies suggest that the endocannabinoid system is altered by seizures and epilepsy.
Research shows that CBD improves seizure control in patients with specific epilepsy syndromes. Seizures can have profound effects on the endocannabinoid system. This is why CBD, through a process known as “external modulation,” can reduce and sometimes stop seizures from happening.
The exact way CBD contributes to a reduction in seizures and affects the Endocannabinoids system (ECS) is still unknown. One theory is that CBD affects the receptors that calm the neurons that fire during a seizure. But there’s still further investigation needed to learn more.
But we do know that CBD oil can have a positive effect on your dog’s seizure activity. If he feels any side effects at all, it will most probably take the form of mild drowsiness.
**Note. Even big pharma has finally recognized the power of CBD oil for seizures. And in June 2018, the FDA approved the first drug containing CBD for the treatment of epilepsy.
CBD Dose For Dogs With Seizures
CBD oil dosage for your dog depends on his size. Smaller dogs require lower dosages, of course, and larger dogs will need more to see an effect. You can make these determinations based on your dog’s weight. It’s best to follow the label directions on the product you buy.
Look for CBD oil with the following features:
- Full spectrum or broad spectrum
- Preferably organic
- Extracted using C02 extraction, without solvents or chemicals
- Manufacturer provides Certificate Of Analysis from a third party lab, showing that the product is what’s claimed on the label, and is free of contaminants, additives or preservatives
Full spectrum CBD oils in tincture form usually work best. If your dog is hard to dose, chewable tablets or treats may be easier. But be aware these products may not contain sufficient levels of CBD to help with seizures.
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CBD oil for seizures in dogs is a natural alternative with minimal side effects and a very promising future.
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Kogan L et al. US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. Front Vet Sci. 2019 Jan 10;5:338.
McGrath S et al. Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy. J Am Vet Med Assoc. 2019 Jun 1;254(11):1301-1308.
Rosenberg EC, et al. Cannabinoids and Epilepsy. Neurotherapeutics. 2015;12(4):747-768.
Perucca E. Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last? J Epilepsy Res. 2017;7(2):61-76. Published 2017 Dec 31.